Xopenex HFA (levalbuterol) is a prescription drug that helps prevent and treat breathing difficulties from sudden airway tightness. The drug comes as an aerosol inhaler. It’s usually used every 4 to 6 hours.

Specifically, Xopenex HFA is used in adults and certain children to help treat or prevent bronchospasm (sudden narrowing of airways) from certain lung conditions or other causes. These include asthma, COPD, allergens, and exercise.

The active ingredient in Xopenex HFA is levalbuterol. Xopenex HFA belongs to a group of drugs called short-acting beta2-adrenergic agonists (SABAs).

This article describes the dosages of Xopenex HFA, as well as its strength and how to use it. To learn more about this medication, see this in-depth article.

Note: Xopenex was also available as a liquid solution for use in a nebulizer machine (as a mist) for bronchospasm. But this form of the drug is no longer available. This article discusses usual dosages of Xopenex HFA aerosol spray. If you have questions about how a dose of Xopenex HFA compares with the Xopenex nebulizer dose, talk with your doctor or pharmacist.

This section describes the usual dosages of Xopenex HFA.

What is Xopenex HFA’s form?

Xopenex HFA is available in a metered-dose inhaler which releases the drug as an aerosol spray puff that you inhale into your lungs.

What strength does Xopenex HFA come in?

Xopenex HFA comes in one strength. It’s available in a 15-gram (g) metered dose inhaler containing 200 puffs (actuations). Each puff delivers 45 micrograms (mcg) of levalbuterol.

What are the usual dosages of Xopenex HFA?

Your doctor will likely start you on the dosage of Xopenex HFA that’s recommended based on the severity of your condition. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The information below describes dosages that are commonly used or recommended. But be sure to use the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs. In some cases, they may adjust your dosage from those shown below.

Dosage for bronchospasm

The typical Xopenex HFA dosage for adults with bronchospasm is 2 puffs inhaled every 4 to 6 hours. In some cases, your doctor may recommend a lower dosage of 1 puff inhaled every 4 hours.

Talk with your doctor or pharmacist if you have questions about your Xopenex dose and frequency.

What’s the dosage of Xopenex HFA for children?

Xopenex HFA is used to help treat and prevent bronchospasm in children ages 4 years and older. The dosage for children is the same as the dosage for adults. See the section just above for details.

For more information about Xopenex HFA’s dosage for children, talk with your child’s pediatrician or a pharmacist.

How to use Xopenex HFA

Xopenex HFA comes as a metered dose inhaler. It is a rescue inhaler used to treat and prevent sudden symptoms of bronchospasm. Each puff releases the active drug which you inhale into your lungs.

You’ll need to “prime” or activate Xopenex HFA before you use it the first time and if you haven’t used it for more than 3 days. To prime the inhaler, release four puffs into the air, away from your face.

For details on how to use the Xopenex HFA inhaler, see the “Instructions for Use” section (beginning on page 20) of the drug’s prescribing information.

For questions about dosage, dosing frequency, the drug’s mechanism of action (how it works), or how long it takes to start working, talk with your doctor or pharmacist.

Is Xopenex HFA used long term?

Yes, Xopenex HFA may be used as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you may use the drug long term.

Do not use more Xopenex HFA than your doctor prescribes, as this can lead to harmful effects.

Symptoms of overdose

Symptoms caused by an overdose can include:

In rare cases, an overdose of Xopenex HFA can be fatal.

What to do in case you use too much Xopenex HFA

Call your doctor right away if you think you’ve inhaled too much Xopenex HFA. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.