Gilotrif (afatinib) is a prescription drug that’s used to treat certain types of non-small cell lung cancer (NSCLC). The drug comes as an oral tablet. It’s usually taken once per day.
Gilotrif is used in adults to treat:
- metastatic NSCLC that has atypical epidermal growth factor receptor (EGFR) genes
- metastatic squamous NSCLC that’s worsened after platinum-based chemotherapy
The active ingredient in Gilotrif is afatinib. Gilotrif belongs to a group of drugs called tyrosine kinase inhibitors.
This article describes the dosages of Gilotrif, as well as its strengths and how to take it. To learn more about Gilotrif, see this in-depth article.
The table below highlights the basics of Gilotrif’s dosage. All doses are listed in milligrams (mg).
| Gilotrif form | Gilotrif strengths | Typical dosage |
|---|---|---|
| oral tablet | • 20 mg • 30 mg • 40 mg | 40 mg once per day |
Keep reading for more details about Gilotrif’s dosage.
What is Gilotrif’s form?
- Gilotrif is available as an oral tablet.
What strengths does Gilotrif come in?
- Gilotrif comes in three strengths:
- 20 mg
- 30 mg
- 40 mg
What are the usual dosages of Gilotrif?
The information below describes dosages that are commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown below.
Dosage for metastatic EGFR-positive NSCLC
The typical Gilotrif dosage for adults with metastatic NSCLC that’s EGFR-positive is 40 mg once per day.
Dosage for metastatic squamous NSCLC
For adults with metastatic squamous NSCLC, the typical dosage of Gilotrif is 40 mg once per day.
How to take Gilotrif
Gilotrif comes as an oral tablet that you swallow once per day. Take the drug on an empty stomach at least 1 hour before or 2 hours after a meal.
Take your dose of Gilotrif around the same time each day. This helps the drug reach a steady level in your body so it can work more effectively.
Gilotrif tablets should be swallowed whole. Do not chew, crush, or split the tablet. If you have trouble swallowing tablets, talk with your doctor or pharmacist.
Is Gilotrif used long term?
Yes, Gilotrif is usually used as a long-term treatment. If you and your doctor determine that it’s safe and effective for your condition, you’ll likely take it long term.
Do not take more Gilotrif than your doctor prescribes, as this can lead to harmful effects.
Symptoms of overdose
Symptoms caused by an overdose can include:
- nausea
- vomiting
- weakness
- dizziness
- headache
- abdominal pain
- high amylase levels in your blood
What to do in case you take too much Gilotrif
Call your doctor right away if you think you’ve taken too much Gilotrif. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.