Dayvigo Interactions: Alcohol, Medications, and Others

An interaction can occur because one substance causes another substance to have a different effect than expected. Interactions can also occur if you have certain health conditions.

Before you start taking Dayvigo, tell your doctor and pharmacist about any prescription, over-the-counter, or other drugs you take. Sharing this information with them may help prevent possible interactions. (To learn whether Dayvigo interacts with herbs or vitamins and supplements, see the “Are there other interactions with Dayvigo?” section below.)

If you have questions about drug interactions that may affect you, talk with your doctor or pharmacist.

The table below lists drugs that may interact with Dayvigo. Keep in mind that this table does not include all drugs that may interact with Dayvigo. For more information about some of these interactions, see the “Drug interactions explained” section below.

Certain health conditions or other factors could raise your risk of harm if you take Dayvigo. In such cases, your doctor may not prescribe Dayvigo for you. These are known as contraindications. Dayvigo has one contraindication, which is described below.

If you have narcolepsy: With narcolepsy, you experience atypical sleep, daytime sleepiness, and “sleep attacks” (overwhelming urges to fall asleep, sometimes suddenly). Dayvigo is prescribed to treat insomnia, which is a condition that causes difficulty sleeping. You should not take Dayvigo if you have narcolepsy, as it may worsen your condition and its symptoms. If you have questions, talk with your doctor.

You should not drink alcohol during your Dayvigo treatment. Doing so can increase the level of Dayvigo in your system. This can raise your risk of side effects, such as problems with balance.

Consuming alcohol can also raise your risk of feeling effects from Dayvigo during the day, such as drowsiness and difficulty concentrating. It can even affect your ability to safely drive, operate machinery, or engage in other activities that require concentration.

If you have questions about avoiding alcohol while taking Dayvigo, talk with your doctor or pharmacist.

Learn more about certain drug interactions that can occur with Dayvigo.

Interaction with benzodiazepines

Dayvigo can interact with benzodiazepines, which are used to treat anxiety, short-term sleep problems, and other conditions.

Examples of benzodiazepine medications include:

• alprazolam (Xanax)
• clonazepam (Klonopin)
• diazepam (Valium, others)
• temazepam (Restoril)

What could happen

Dayvigo and benzodiazepines can both cause central nervous system (CNS) depression. Taking these drugs together can raise your risk of this side effect.

What you can do

If you use Dayvigo with a benzodiazepine, your doctor may prescribe a lower dose of Dayvigo and the benzodiazepine for you. You should not take a higher dose of either medication than your doctor prescribes. Your doctor may also suggest stopping treatment with the benzodiazepine if you’re taking it to treat insomnia, as Dayvigo is prescribed to treat this condition.

If you take Dayvigo and a benzodiazepine together, tell your doctor right away if you have symptoms of CNS depression. These may include slurred speech, drowsiness, and difficulty with coordination and making decisions.

If you have questions about taking Dayvigo with a benzodiazepine, talk with your doctor or pharmacist.

Interaction with other drugs that treat insomnia

Dayvigo can interact with other drugs used to treat insomnia. Examples include:

• eszopiclone (Lunesta)
• zolpidem (Ambien)
• suvorexant (Belsomra)
• ramelteon (Rozerem)

What could happen

Dayvigo is prescribed to treat insomnia. Other drugs used to treat insomnia and Dayvigo can cause some similar side effects, including CNS depression. Symptoms of CNS depression include drowsiness, slurred speech, and difficulty with coordination and making decisions. Taking Dayvigo with another drug that treats insomnia raises your risk of these effects.

What you can do

Your doctor will likely avoid prescribing Dayvigo with another insomnia drug. This combination raises the risk of side effects, and it isn’t likely to be more effective for your insomnia. This is particularly true for “Z-drugs” such as zolpidem and eszopiclone, according to the FDA.

Talk with your doctor or pharmacist if you have other questions about this interaction.

Dayvigo may have other interactions. They could occur with supplements, foods, vaccines, or even lab tests. See below for details. Note that the information below does not include all other possible interactions with Dayvigo.

Does Dayvigo interact with supplements?

Before you start taking Dayvigo, talk with your doctor and pharmacist about any herbs or vitamins and supplements you take. Sharing this information with them may help you avoid possible interactions.

If you have questions about interactions that may affect you, talk with your doctor or pharmacist.

Dayvigo interactions with herbs

Dayvigo can interact with St. John’s wort, which is used to manage symptoms of depression and other conditions. Taking St. John’s wort can make Dayvigo less effective. Your doctor will likely suggest that you do not use St. John’s wort with Dayvigo due to this interaction.

For this reason, check with your doctor or pharmacist before taking St. John’s wort or other herbal supplements while taking Dayvigo.

Dayvigo interactions with vitamins

There are currently no reports of Dayvigo interacting with vitamins. But this doesn’t mean that vitamin interactions won’t be recognized in the future.

For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products while taking Dayvigo.

Does Dayvigo interact with food?

Grapefruit and grapefruit juice can interact with Dayvigo. Consuming them with Dayvigo can raise your risk of side effects from the drug.

Your doctor will likely recommend that you avoid consuming grapefruit or grapefruit juice while you’re taking Dayvigo. You can talk with your doctor or pharmacist if you have other questions about this interaction.

Does Dayvigo interact with vaccines?

There are currently no reports of Dayvigo interacting with vaccines. If you have questions about getting certain vaccines during your Dayvigo treatment, talk with your doctor.

Does Dayvigo interact with lab tests?

There are currently no reports of Dayvigo interacting with lab tests. If you have questions about having certain lab tests during your treatment with Dayvigo, talk with the healthcare professional ordering the test.

Does Dayvigo interact with cannabis or CBD?

Cannabis(commonly called marijuana) and cannabis products, such as cannabidiol (CBD), have been specifically reported to interact with Dayvigo.

Cannabis can have a depressant effect, including CNS depression. Dayvigo also causes CNS depression, so taking cannabis could worsen these effects. Examples of symptoms this interaction could cause include difficulty with balance and coordination, slurred speech, and difficulty making decisions.

Before you start Dayvigo treatment, tell your doctor and pharmacist if you use cannabis. By sharing this information with them, you may help prevent possible interactions.

Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees.

Certain medical conditions or other health factors may raise the risk of interactions with Dayvigo. Before taking Dayvigo, talk with your doctor about your health history. They’ll determine whether Dayvigo is right for you.

Health conditions or other factors that might interact with Dayvigo include:

Breathing condition, such as chronic obstructive pulmonary disease (COPD): If you have a breathing condition such as COPD or sleep apnea, Dayvigo could worsen symptoms of it. Your doctor can help determine whether Dayvigo is safe for you to take.

Liver condition: Having a liver condition such as cirrhosis can cause the level of Dayvigo in your system to build up. This can raise your risk for side effects from the drug. Depending on how severe your liver condition is, your doctor may prescribe a lower Dayvigo dosage. Or they may determine that it’s not safe for you to take Dayvigo.

Narcolepsy: You should not take Dayvigo if you have narcolepsy or any other condition that may cause you to suddenly fall asleep during the day. Dayvigo is prescribed to treat insomnia, so it may worsen your condition and its symptoms. If you have questions, talk with your doctor.

Substance use disorder: Dayvigo is a controlled substance. This means it has an approved medical use but may be misused for other purposes. If you’ve had a substance use disorder before, such as opioid use disorder, talk with your doctor. They can determine whether it’s safe for you to take Dayvigo.

Pregnancy: It’s not known whether Dayvigo is safe to take during pregnancy. If you’re pregnant or planning a pregnancy, talk with your doctor before taking Dayvigo.

If you do use Dayvigo while pregnant, consider enrolling in the drug’s pregnancy registry. This registry collects details about pregnancy issues reported with Dayvigo. To learn more, visit the registry website, call 1-866-961-2388, or talk with your doctor.

Breastfeeding: It’s not known whether it’s safe to use Dayvigo while breastfeeding. The drug passes into breast milk, but it isn’t known whether the drug may cause side effects in a child who is breastfed. If you’re breastfeeding or planning to do so, talk with your doctor about your options.

Allergic reaction: If you’ve had an allergic reaction to Dayvigo or any of its ingredients, your doctor will likely not prescribe Dayvigo. This is because taking the drug could cause another allergic reaction. You can ask your doctor about other treatments that may be better choices for you.

Depression or suicidal thoughts: Dayvigo can cause worsening symptoms of depression, suicidal thoughts, or other mental health conditions. Before you start taking Dayvigo, talk with your doctor about any mental health conditions you may have experienced. If they prescribe Dayvigo for you, they’ll likely want to monitor your mental health closely during your treatment.

Taking certain steps can help you avoid interactions with Dayvigo. Before starting treatment, talk with your doctor and pharmacist. Things to discuss with them include:

• whether you drink alcohol or use cannabis
• other medications you take, as well as any vitamins, supplements, and herbs (they can also help you fill out a medication list)
• what to do if you start taking a new drug during your Dayvigo treatment

It’s also important to understand Dayvigo’s label and other paperwork that may come with the drug. Colored stickers that describe interactions may be on the label. The paperwork (sometimes called the patient package insert or medication guide) may have other details about interactions. (If you did not get paperwork with Dayvigo, ask your pharmacist to print a copy for you.)

If you have difficulty reading or understanding this information, your doctor or pharmacist can help.

Taking Dayvigo exactly as prescribed can also help prevent interactions.

Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.