Dosage Details for Amjevita

This section describes the usual dosages of Amjevita. Keep reading to learn more.

What are Amjevita’s forms?

Amjevita is available as a liquid solution in two forms, each given as injections under your skin:

• prefilled SureClick auto-injector
• prefilled glass syringe

Each form provides a single dose.

What strengths does Amjevita come in?

Amjevita’s prefilled SureClick auto-injector comes in these strengths:

• 80 milligrams (mg) per 0.8 milliliter (mL) (80 mg/0.8 mL)
• 40 mg/0.8 mL
• 40 mg/0.4 mL

Amjevita’s prefilled glass syringe comes in these strengths:

• 80 mg/0.8 mL
• 40 mg/0.8 mL
• 40 mg/0.4 mL
• 20 mg/0.4 mL
• 20 mg/0.2 mL
• 10 mg/0.2 mL

What are the usual dosages of Amjevita in adults?

Your doctor will likely start by prescribing the recommended dosage of Amjevita for the condition it’s treating.

The information below describes dosages that are commonly prescribed or recommended. But be sure to follow the dosage your doctor prescribes. They’ll determine the best dosage to fit your needs.

Dosage for plaque psoriasis

For plaque psoriasis in adults, the usual dosage of Amjevita is 80 mg as a first dose. Then, 1 week later, your doctor will change the dosage to 40 mg every 2 weeks.

Note: It’s not known whether treatment with adalimumab for moderate to severe plaque psoriasis is effective for longer than 1 year. (Amjevita’s active ingredient is adalimumab.)

Dosage for hidradenitis suppurativa

For hidradenitis suppurativa in adults, the usual dosage of Amjevita begins with 160 mg on day 1 of treatment. This may be given as one dose or split into two doses (80 mg on day 1 and 80 mg on day 2).

Then, 2 weeks later on day 15, your doctor will change the dose to 80 mg. And 2 weeks after that on day 29, they’ll change the dosage to either 40 mg every week or 80 mg every 2 weeks.

Your doctor will determine the Amjevita dose and dosing schedule that works best for you.

Dosage for uveitis

For uveitis in adults, the usual starting dosage of Amjevita is 80 mg on day 1 of treatment. Then, 1 week later, your doctor will change the dosage to 40 mg every 2 weeks.

Dosage for rheumatoid arthritis

For rheumatoid arthritis in adults, the usual dosage of Amjevita is 40 mg every 2 weeks.

In some cases, if you’re not taking methotrexate for rheumatoid arthritis, your doctor may raise your Amjevita dosage. In this case, the Amjevita dosage may be 40 mg every week or 80 mg every 2 weeks.

Your doctor will determine the best dosage to fit your needs.

Dosage for psoriatic arthritis

For psoriatic arthritis in adults, the usual dosage of Amjevita is 40 mg every 2 weeks.

Dosage for ankylosing spondylitis

For ankylosing spondylitis in adults, the usual dosage of Amjevita is 40 mg every 2 weeks.

Dosage for Crohn’s disease

For Crohn’s disease in adults, the usual starting dosage of Amjevita is 160 mg on day 1 of treatment. This may be given as one dose or split into two doses on consecutive days. For example, it could be split into 80 mg on day 1 and 80 mg on day 2.

Then, 2 weeks later on day 15, your doctor will change the dose to 80 mg. And 2 weeks after that on day 29, they will change the dosage to 40 mg every 2 weeks.

Dosage for ulcerative colitis

For ulcerative colitis in adults, the usual starting dosage of Amjevita is 160 mg on day 1 of treatment. This may be given as one dose or split into two doses on consecutive days. For example, it could be split into 80 mg on day 1 and 80 mg on day 2.

Then, 2 weeks later on day 15, your doctor will change the dose to 80 mg. And 2 weeks later on day 29, they will change the dosage to 40 mg every 2 weeks.

Your doctor will monitor how your body responds to treatment with Amjevita. If you don’t experience remission (no symptoms) from UC after 8 weeks of treatment, they may stop Amjevita.

Talk with your doctor if you have questions about your dosage and treatment with Amjevita.

What’s the dosage of Amjevita for children?

Amjevita is prescribed to treat Crohn’s disease in children ages 6 years and older. Amjevita is also prescribed to help treat juvenile idiopathic arthritis in children ages 2 years and older.

Dosage for Crohn’s disease

For children with Crohn’s disease, the Amjevita dosage is based on their body weight in kilograms (kg). For reference, 1 kg is about 2.2 pounds (lb).

The dosage for children weighing 17 kg to less than 40 kg (about 37 lb to less than 88 lb) is:

• 80 mg on day 1 of treatment
• 40 mg on day 15 of treatment
• 20 mg every 2 weeks starting on day 29 of treatment and beyond

The dosage for children weighing 40 kg or more (about 88 lb or more) is:

• 160 mg on day 1 of treatment (may be given as one dose or split into two doses on consecutive days)
• 80 mg on day 15 of treatment
• 40 mg every 2 weeks starting on day 29 of treatment and beyond

Dosage for juvenile idiopathic arthritis

For children with juvenile idiopathic arthritis, the Amjevita dosage is based on their body weight in kg. For reference, 1 kg is about 2.2 lb. The dosages by weight are as follows:

• weight of 10 kg to less than 15 kg (about 22 lb to less than 33 lb): 10 mg every 2 weeks
• weight of 15 kg to less than 30 kg (about 33 lb to less than 66 lb): 20 mg every 2 weeks
• weight of 30 kg or more (about 66 lb or more): 40 mg every 2 weeks

For more information about Amjevita’s dosages for children, talk with your child’s doctor or a pharmacist.

Is Amjevita used long term?

Amjevita might be prescribed long term. The length of treatment with Amjevita your doctor recommends will depend on several factors. These include:

• the type and severity of the condition Amjevita is treating
• your body’s response to treatment
• other medications you may be taking

If you have questions about how long your treatment with Amjevita will last, talk with your doctor.

The dosage of Amjevita you’re prescribed may depend on several factors. These include:

• the type and severity of the condition the drug is treating
• your age
• body weight (in children)
• other medications you may be taking

Amjevita is available as a liquid solution that’s given as an injection under the skin.

You might receive doses of Amjevita at your doctor’s office or a clinic. Or you might be able to give them to yourself or your child at home. Your doctor or another healthcare professional will show you how to give the injections.

When giving doses at home, you’ll inject Amjevita under the skin on the front of your thigh or abdomen. Be sure to rotate the area where you inject Amjevita. This means to use a different area than what you used for the last dose for every injection.

Do not inject the medication in areas that are discolored or deepened in color, tender, hard, or bruised. And do not inject the medication into areas that are scarred or have stretch marks.

You can learn more about giving injections of Amjevita with these step-by-step instructions:

• SureClick auto-injector
• prefilled syringe

For information on the expiration, storage, and disposal of Amjevita, talk with your doctor or pharmacist.

Accessible drug containers and labels

Some pharmacies provide medication labels that:

• have large print
• use braille
• feature a code you can scan with a smartphone to change the text to audio

Your doctor or pharmacist may be able to recommend pharmacies that offer these accessibility features if your current pharmacy doesn’t.

If you miss a dose of Amjevita, inject it as soon as you remember. But if it’s almost time for your next dose, skip the missed dose and inject your next dose at its usual time. If you’re not sure whether you should inject a missed dose, talk with your doctor or pharmacist.

To help you remember to inject doses of Amjevita on time, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.

If you miss an appointment to receive Amjevita, call your doctor’s office or clinic promptly to reschedule. You can also use a reminder app on your phone or an alarm to help you remember appointments.

Do not inject more Amjevita than your doctor prescribes, as this can lead to harmful effects.

What to do in case you inject too much Amjevita

Call your doctor right away if you think you’ve injected too much Amjevita. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.

Below are answers to some commonly asked questions about Amjevita’s dosage.

Is Amjevita’s dosage similar to the dosage of Humira?

Yes, it is. The forms, strengths, doses, and how often you give each drug are similar.

Both Amjevita and the brand-name drug Humira (adalimumab) are biologic drugs. Amjevita is the biosimilar version of Humira.

Biologics and biosimilars are made from parts of living organisms. Biosimilars are similar to generic drugs. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs. Biosimilar versions are generally less expensive than brand-name biologic medications.

Amjevita and Humira are both approved to treat the same conditions in adults. But Humira is also approved to treat ulcerative colitis, hidradenitis suppurativa, and uveitis in children as well as adults.

Your doctor will prescribe the drug and the dosage that’s right for you.

To learn more about how these drugs compare, talk with your doctor.

How long does it take for Amjevita to start working?

Amjevita starts to work after your first dose. But the condition it’s treating and its severity affect how long it takes to ease your symptoms. It may take several weeks for your symptoms to lessen. Your doctor will monitor you during treatment to check whether the drug is working for your condition.

If you have other questions about what to expect from your Amjevita treatment, talk with your doctor.

The sections above describe the usual dosages provided by Amjevita’s drugmaker. If your doctor recommends this drug, they’ll prescribe the dosage that’s right for you.

Remember, you should not change your dosage of Amjevita without your doctor’s recommendation. Inject Amjevita exactly as prescribed. Talk with your doctor if you have questions or concerns about your current dosage.

Here are some examples of questions you may want to ask your doctor:

• Will you change my child’s dosage of Amjevita if they lose weight?
• How does the dosage of Amjevita compare with the dosage of Taltz (ixekizumab)?
• Will I need a dosage adjustment for Amjevita if I have side effects from the medication?

To learn more about Amjevita, see this “All About Amjevita” article.

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.